#H19 #influenza A virus exhibits #species-specific #MHC class II #receptor usage, Cell Host Microbe: https://www.cell.com/cell-host-microbe/abstract/S1931-3128(24)00190-2?rss=yes

Influenza A virus H19 subtype does not bind the canonical receptor #sialic acid. H19 utilizes MHC class II #proteins from distinct species for host cell entry.
Mutating the putative canonical RBS of H19 restores sialic acid dependency. Residues in the MHC class II α chain confer species-specific entry of H19.

#H19 #influenza A virus exhibits #species-specific #MHC class II #receptor usage, Cell Host Microbe, https://www.sciencedirect.com/science/article/abs/pii/S1931312824001902?via%3Dihub

H19 utilizes MHC class II proteins from distinct species for host cell entry. Mutating the putative canonical RBS of H19 restores sialic acid dependency. Residues in the MHC class II α chain confer species-specific entry of H19.

Pipeline release! nf-core/mhcquant v2.6.0 - MHCquant 2.6.0 - Mr Bob!

Please see the changelog: https://github.com/nf-core/mhcquant/releases/tag/2.6.0

#dda #immunopeptidomics #mass-spectrometry #mhc #openms #peptides #nfcore #openscience #nextflow #bioinformatics

Pipeline release! nf-core/epitopeprediction v2.3.1 - v2.3.1 - Oesterberg - 2024-05-17!

Please see the changelog: https://github.com/nf-core/epitopeprediction/releases/tag/2.3.1

#epitope #epitope-prediction #mhc-binding-prediction #nfcore #openscience #nextflow #bioinformatics

Grußwort der Autorin und Wissenschaftlerin - Dr. Julia Shaw

https://www.youtube.com/watch?v=_P5cAaFlvW8

DNA sensing via the #cGAS/STING pathway regulates #immunoproteasome function and #MHC class I #antigen presentation to promote #Tcell activation - with implications for the pathology of idiopathic pulmonary fibrosis

Silke Meiners et al ForschungszentrumBorstel@norden.social

https://www.embopress.org/doi/10.15252/embj.2022110597

How #COVID actively suppresses and evades your #immune system [Part 1]

This thread highlights multiple methods that the virus uses to help keep #reinfecting people including #MHC-I and #interferon #suppression, #evasion of Natural Killer (NK) cells, and reprogramming of #monocytes. 1/

The one page web view is available here: https://pingthread.com/thread/1611333222419566594

prof Akiko Iwasaki

#MHC-I
#downregulation by #SarsCov2

#immunology #mechanism

https://threadreaderapp.com/thread/1607446922599763968.html

20. #Todestag - Am 29. September 2002 starb in #Berlin der #Historiker, #Publizist und #Schwulen-#Aktivist Hans-Georg #stümke (auch bekannt als Elvira #Klöppelschuh )
#UHA #mhc #Schwulenbewegung
https://www.2mecs.de/wp/2009/09/hans-georg-stuemke/